Post-industrial neighbourhood east of the Florenc station, rebuilt after the 2002 floods. Eska, Stangl, Antonin Bakery and Muj Salek Kavy live here.
Eska in Karlin holds a Michelin Bib Gourmand. The Ambiente group rebuilt a 19th-century Karlin factory into a bakery-restaurant cooking modern Czech, all day long.
Signature: Old bread sourdough, Fermented potato
Order: Old bread with butter, then the kitchen's daily fermentation.
Stangl took a Michelin star plus a Green Star in the 2025 guide. Above Eska bakery in Karlin, Martin Stangl cooks open-kitchen tasting menus rooted in Czech terroir.
Order: The five-course tasting; book the Saturday breakfast version.
Eska is the Ambiente group's Karlin bakery-restaurant, holding a Michelin Bib Gourmand and serving a Czech-rooted modern menu from a converted 19th-century factory.
Order: Old bread sourdough with butter, then the fermented potato dish.
Lokal Hamburk is the Karlin outpost of the Ambiente pub chain, on the site of a 19th-century river-harbour inn. Pilsner from tank, honest Czech cooking, evening crowd.
Signature: Vepro-knedlo-zelo, Tank Pilsner
Order: Vepro-knedlo-zelo; pour from tank.
Muj Salek Kavy translates as my cup of coffee. The Doubleshot-run room in Karlin was Prague's first serious specialty cafe, serving breakfasts and changing single-origin pours.
Signature drink: Doubleshot espresso
Tip: Reservations save the day at brunch; the breakfast plate is the kitchen's tightest.
Eska Karlin is the original Ambiente bakery-cafe-restaurant in a converted 19th-century factory. The all-day room serves bread 33 from the bakery counter and a full breakfast menu.
Signature drink: Black filter
Tip: The Stangl tasting room is upstairs; book in advance for that experience.
Eska's Karlin bakery counter sells bread 33, the city's most cited sourdough, plus kolache and laminated pastries. Bake schedule is built around the upstairs restaurant menu.
Tip: Bread 33 sells out by lunch on Saturday; sweet kolache last longer.
Worth the queue: Bread 33, three-stage rye on beech wood
Antoninovo Pekarstvi opened the first of its six city-wide bakeries in Karlin in 2014. Wheat-rye and potato sourdough loaves, all baked on-site, plus made-up chlebicky and soups.
Tip: The decorated chlebicky are made up at the counter; ask for a flight to-go.
Worth the queue: Potato sourdough loaf
Alf and Bet roasts specialty coffee and bakes artisan bread out of an old industrial workshop in Liben-Karlin. Their beans supply EMA Espresso Bar across the city.
Tip: Order through EMA espresso bars rather than visiting the roastery directly.
Sources from: Ethiopia, Brazil, Guatemala, Rwanda
How they serve: Espresso, Filter, Whole bean retail, Subscription
EMA's Karlin cafe doubles as their main Prague specialty coffee shopfront. Beans roasted by partner Alf and Bet are served with fresh bread, sandwiches and pastries from the same bakery.
Tip: The Florenc original is closer to public transport; same beans, smaller crowd.
Sources from: Ethiopia, Colombia, Rwanda
How they serve: Espresso, Filter, Whole bean retail
Veltlin in Karlin is Bogdan Trojak's natural-wine bar, focused on what he calls authentic wines from the old Habsburg empire. No list, just bottles opened by mood and pairing.
Signature pour: Moravian pet-nat by the glass
Wine focus: Authentic wines from the former Habsburg empire, Moravia heavy
Food: Cheese, sardines, small plates
Tip: Trust the staff; ask for a Moravian flight and order the sardines.
Lokal Hamburk in Karlin is the river-harbour-themed Ambiente Lokal, the most neighbourhood-feeling of the chain. Tank Pilsner, big windows, the office crowd settles in evenings.
Signature drink: Tank Pilsner Urquell
Food: Czech pub menu
Tip: The terrace seats in summer go fast; book ahead Friday onward.
Dva Kohouti in Karlin is the Ambiente group's brewery joint-venture with Matuska. The Karlin courtyard taproom pours their own lager and craft ales next to a working brewhouse.
Tip: The 12-degree lager is the house pour; the back beer garden in summer.
The Karlin Street Food Festival is the city's largest one-day street food fair, an annual neighbourhood event on Karlinske namesti with around 40 food stalls, DJs and live music.
Tip: Cashless; come hungry, stalls are tightly packed, plates designed to share.
Antoninovo Pekarstvi's Karlin bakery sells made-up chlebicky at 45 CZK each plus daily soups. Two chlebicky plus a soup is lunch for under 200 CZK, all made on the premises.
Try: Three chlebicky plus soup
Tip: Sit at the counter with a coffee; the egg-and-beetroot pair is the smart order.
Muj Salek Kavy in Karlin is the Doubleshot-run brunch spot Prague locals book ahead. Egg dishes, the daily pastry, single-origin filter coffee, a calm laptop-friendly back room.
Order: House breakfast plate with single-origin pour
Tip: Reservations save the day; the breakfast plate is the kitchen's tightest piece.
Eska Karlin runs an all-day brunch in the bakery-restaurant: bread 33 sourdough toast, eggs, fermented vegetables and the kitchen's morning pastry plate. Industrial Karlin room.
Order: Bread 33 toast, eggs, fermented Czech vegetables
Tip: Book Saturday brunch in advance; bread 33 sells out by noon weekly.