Brewery in Key West

The Waterfront Brewery ★ 4.3

The Waterfront Brewery brews Crazy Lady Honey Blonde with local Keez Beez honey beside Key West's bight, the largest craft operation in the Keys.

OrderCrazy Lady Honey Blonde at the harbour-view rail

TipThe full seafood menu makes it a lunch stop as much as a taproom; the tap list rotates, so ask what left the tanks last.

First Flight Island Restaurant & Brewery ★ 4.2

First Flight serves chef-driven plates and house beer in the 1927 building where Pan Am sold its first tickets, under a Key West garden tree canopy.

OrderThe local catch with a Main Squeeze citrus wheat ale

TipAsk for the Tree-Top deck or the Crash Bar, whose counter is a riveted aluminium airplane wing.

Southernmost Pint Brewpub ★ 4.1

Southernmost Pint pours up to 18 house taps from its Blast Beer Co brewery on Front Street in Key West, brewing every beer gluten-reduced or removed.

OrderA Save the Day IPA flight under the projection screen

TipThe 2026 brewery guide notes a dedicated gluten-free kitchen alongside the gluten-reduced tanks, rare for a brewpub anywhere.

Cayo Hueso Brewing ★ 4.1

Cayo Hueso Brewing pours El Hemingway pale ale in a Stock Island beer garden near Key West, a Brewers Association certified-independent taproom.

OrderEl Hemingway pale ale with a Roostica pizza from next door

TipRoostica's wood-fired pies serve the beer garden, and dogs are welcome outside; it is the locals' taproom of the four.

Cayo Hueso Brewing ★ 4.1

Cayo Hueso Brewing pours El Hemingway pale ale in a Stock Island beer garden near Key West, a Brewers Association certified-independent taproom.

TipRoostica's wood-fired pies serve the beer garden, and dogs are welcome outside; it is the locals' taproom of the four.