The Waterfront Brewery is a brewery in Historic Seaport, Key West.
Editorially verified August 21, 2026 by Lewis Vaughan, TableJourney editor. Source.
Must order: Crazy Lady Honey Blonde at the harbour-view rail
Tip: The full seafood menu makes it a lunch stop as much as a taproom; the tap list rotates, so ask what left the tanks last.
Address: 201 William Street, Key West, FL 33040
First Flight serves chef-driven plates and house beer in the 1927 building where Pan Am sold its first tickets, under a Key West garden tree canopy.
Order: The local catch with a Main Squeeze citrus wheat ale
Tip: Ask for the Tree-Top deck or the Crash Bar, whose counter is a riveted aluminium airplane wing.
Southernmost Pint pours up to 18 house taps from its Blast Beer Co brewery on Front Street in Key West, brewing every beer gluten-reduced or removed.
Order: A Save the Day IPA flight under the projection screen
Tip: The 2026 brewery guide notes a dedicated gluten-free kitchen alongside the gluten-reduced tanks, rare for a brewpub anywhere.
Cayo Hueso Brewing pours El Hemingway pale ale in a Stock Island beer garden near Key West, a Brewers Association certified-independent taproom.
Order: El Hemingway pale ale with a Roostica pizza from next door
Tip: Roostica's wood-fired pies serve the beer garden, and dogs are welcome outside; it is the locals' taproom of the four.
