centro-historicoTue-Sat 18:00-23:00
El Destilado on Cinco de Mayo is the natural-Mexican-wine and mezcal-pairing programme alongside the tasting menu, with a deep Valle de Guadalupe bottle list.
Signature pour: Bichi Listan Negro by the glass
Wine focus: Natural Mexican wines and mezcal
Food: Tasting menu
centro-historicoWed-Sat 18:00-00:30
La Popular on Garcia Vigil is a restaurant, bar and gallery with a natural-wine list and a tight kitchen of small plates, a fixture of the Oaxaca scene.
Signature pour: Mexican orange wine by the glass
Wine focus: Natural and Mexican wines
Food: Snacks and small plates
jalatlacoTue-Sat 17:00-23:00
Neta Tasting Room in Jalatlaco is the Neta Spirits showroom on Cinco de Mayo 506, with mezcal flights, natural wines and small plates in quiet evenings.
Signature pour: Neta Spirits flight
Wine focus: Mezcal-led with natural wines
Food: Snacks
centro-historicoMon, Wed-Fri 13:00-00:00; Sat 13:00-00:00
Sabina Sabe on Cinco de Mayo 209 is named for Maria Sabina, a cocktail bar with a vast mezcal collection, natural wines and local-ingredient small plates.
Signature pour: Sabina Sabe house cocktail
Wine focus: Mezcal-cocktails with wine by the glass
Food: Small plates
centro-historicoMon-Sat 16:00-01:00
Selva on Macedonio Alcala is the 50 Best Discovery cocktail bar with creative Oaxacan-ingredient drinks and mezcals from small distilleries on a tight bar.
Signature pour: Selva house cocktail
Wine focus: Mezcal and natural wines
Food: Snacks
centro-historicoMon-Sat 17:00-01:00
Comala on Pino Suarez runs a small Mexican wine list with Casa Madero, Bichi and Cuna de Tierra alongside the in-house mezcal cocktails and the courtyard.
Signature pour: Casa Madero by the glass
Wine focus: Mexican wines and mezcal
Food: Snacks and Oaxacan plates
centro-historicoTue-Sat 17:00-00:30
Mezcalogia on Garcia Vigil pairs Casa Cortes mezcals (El Jolgorio, Nuestra Soledad) with a tight Mexican wine list and a small kitchen of Oaxacan plates.
Signature pour: El Jolgorio Tobala
Wine focus: Mezcal with Mexican wine by the glass
Food: Oaxacan plates
centro-historicoMon-Sat 13:00-18:00, by appointment
Mezcaloteca on Reforma is the appointment-only mezcal library with 100-plus family producers for educational flights and a small dry-snack pairing service.
Signature pour: Family-producer mezcal flight
Wine focus: Mezcal flights by appointment
Food: No food
centro-historicoMon-Sat 14:00-23:00
In Situ on Vicente Guerrero is Ulises Torrentera's mezcaleria with 180-plus mezcals, often poured by the author himself, and a small snack program for long.
Signature pour: Ulises Torrentera-curated flight
Wine focus: Mezcal-only, no wine
Food: Bar snacks