About an hour west of Frankfurt by regional trainRegional trains from Frankfurt Hauptbahnhof along the Rheingau line
Famous for: Riesling taverns off the Drosselgasse and vineyard walks above the Rhine
Rüdesheim packs the Rheingau's wine culture into one riverside town: Drosselgasse taverns, Riesling estates and vineyard paths over the Rhine.
About an hour from Frankfurt via EltvilleRegional train to Eltville, then bus or taxi into the Eberbach valley
Famous for: Wine tastings in a 12th-century Cistercian monastery cellar
Kloster Eberbach pairs one of Europe's best-kept medieval monasteries with a working state winery, tastings daily in the vinothek until 19:00.
About 40 minutes from Frankfurt by S-BahnS-Bahn or regional trains from Frankfurt Hauptbahnhof to Mainz Hbf
Famous for: Weekly market mornings and wine taverns in the old town lanes
Mainz styles itself a wine capital, and earns it: old-town wine taverns, Rheinhessen growers and a weekly market that doubles as a party twice a week.
About 40 minutes from Frankfurt by S-BahnS-Bahn from Frankfurt Hauptbahnhof to Wiesbaden Hbf
Famous for: Kaffeehaus culture, Maldaners coffee and Rheingau wine on the doorstep
Wiesbaden does the elegant spa-town food day: Kaffeehaus stops like Maldaners Coffee Roasters, smart dining and Rheingau wine nearby, one S-Bahn ride away.
About 30 minutes from Frankfurt by S-BahnS-Bahn from Frankfurt Hauptbahnhof toward Wiesbaden, stop Hochheim
Famous for: Rheingau wine estates and vinothek tastings above the Main
Hochheim is the closest real wine town to Frankfurt, its estates and Vinothek pouring the Rieslings that named English Hock, a short S-Bahn hop from the city.
About 20 minutes from Frankfurt by regional trainRegional trains from Frankfurt Hauptbahnhof to Darmstadt Hbf
Famous for: Mathildenhöhe art-nouveau hill, a September wine festival and the Ratskeller
Darmstadt adds a food excuse to its UNESCO Mathildenhöhe: a September wine festival, market squares and the Ratskeller, twenty minutes away.
About 40 minutes east of FrankfurtRegional trains from Frankfurt toward Aschaffenburg, stop Seligenstadt
Famous for: Half-timbered old town cafes by the Main and monastery gardens
Seligenstadt, the Einhard town upriver from Frankfurt, does the slow half-timbered day: old-town cafes, monastery gardens, Main-side walks and ferry rides.