Pueblan$$$centro-historicoMon-Sat 08:00-23:00; Sun 08:00-18:00Book 2 to 4 days ahead
La Casa del Mendrugo cooks mole poblano and pipian verde inside a former Jesuit college on 4 Sur in Puebla, with a museum and a jazz room attached.
Tip: The mole here runs about 190 pesos and the ticket includes the museum, which is a rare pairing in the Centro Historico.
Pueblan$$$centro-historicoDaily 08:00-22:30Book 2 to 5 days ahead
Restaurante Casareyna holds a 2026 Michelin Bib Gourmand in Puebla, serving a four-mole tasting plate under Talavera vaults on Privada 2 Oriente.
Tip: Mole plates land between 205 and 245 pesos, which is what the 2026 Bib Gourmand is recognising more than the dining room.
Pueblan$$los-remediosDaily 13:00-22:30
Antojitos Mellos is the weekend mole and pipian stop in Barrio de los Remedios, Puebla, with pozole and mole de panza on the board the rest of the week.
Why locals love it: Weekend-only mole and pipián in Barrio de los Remedios, far enough from the Zocalo that the queue stays local.
Tip: Mole and pipián are cooked on Saturday and Sunday only, so a weekday visit gets pozole and mole de panza instead.
Pueblan$$centro-historicoDaily 08:00-24:00Until 00:00 daily
Comal looks straight at Puebla cathedral from 16 de Septiembre, cooking blue-corn chilaquiles, chanclas, pelonas and mole poblano from breakfast to midnight.
Try: Chanclas and mole poblano
Tip: The kitchen runs to midnight seven days a week, which is unusual for a Centro dining room of this quality.
Pueblan$$$$la-noriaMon-Wed 08:00-23:30; Thu-Sat 13:30-23:30; Sun 13:30-18:00Book 1 week in nogada season ahead
Restaurante La Noria works the grounds of an old hacienda in Puebla, cooking mole, pipian and huazontles, plus chiles en nogada from July to September.
Tip: From July to September the hacienda fills with chiles en nogada bookings, so reserve at least a week out in August.