Food day trips from St. Louis

Defiance (Missouri Wine Country)

  • ★ 4.0
  • 40 minutes west by car
  • Day trip from St. Louis

A small river-bluff town, Defiance packs several wineries, a brewery and a distillery within a couple of miles, the closest wine country to St. Louis.

Checked by against its source.

The trip

Famous for
A compact cluster of wineries, a brewery and a distillery
Getting there
Drive west on I-64 then Highway 94 to Defiance
Distance
40 minutes west by car of St. Louis

Directions from St. Louis

Make a night of it

Hotels in Defiance

Stay over and eat there twice

Expedia

See hotels

Tours and tastings that visit Defiance (Missouri Wine Country)

See all 95 food experiences in St. Louis

More food day trips from St. Louis

See all
Kimmswick (Blue Owl pie)30 minutes south by car★ 4.1Ste. Genevieve1 hour south by car★ 4.0Edwardsville, Illinois25 minutes northeast by car★ 3.8Washington, Missouri1 hour west by car★ 3.8Kirkwood (Global Foods)20 minutes southwest by car★ 3.9Augusta (Missouri Wine Country)45 minutes west by car★ 4.1

Keep exploring