Modern Mexican$$$$southtownWed-Sat, two seatings by reservation
Mixtli is San Antonio's first Michelin-starred restaurant, where chefs Diego Galicia and Rico Torres build a rotating tasting menu around one Mexican region.
Order: Whatever region the rotating tasting menu is exploring this season.
Tip: The menu changes every several weeks and focuses on one region of Mexico at a time. Book on Tock well ahead; seats are limited.
Asian American$$$pearlLunch and dinner, closed Monday
Chef Jennifer Dobbertin's New Asian American restaurant sits in the historic Mueller House at the Pearl, drawing on her Chinese-American heritage.
Order: Crab rangoon dip, Taiwanese popcorn chicken and the family-style noodles.
Tip: The patio and the funky Mueller House interior are both worth requesting. Cocktails lean playful; ask for the seasonal special.
New American$$$alamo-heightsDinner Tue-Sat, closed Sun-Mon
Chef John Russ and Elise Russ run Clementine in Castle Hills, a chef-driven New American room that has been one of San Antonio's most ambitious kitchens.
Order: The Feed Me tasting option, which lets the kitchen build the meal for you.
Tip: Order the Feed Me option and let the kitchen drive. The dining room is small, so book ahead on OpenTable.
Texas coastal$$$pearlLunch and dinner daily
Chef Jeff Balfour's Southerleigh brews 15 beers in-house on the ground floor of the Pearl Brewery and pairs them with Texas coastal cooking.
Order: Fried chicken, Gulf snapper and a pint of the house-brewed beer.
Tip: Sit near the gleaming brew tanks and order the fried chicken with the house pilsner. The patio fills fast on Pearl market mornings.
Mediterranean$$$pearlDinner, closed Monday
Ladino is a Sephardic-leaning Mediterranean room at the Pearl built for family sharing, where wood-grilled meats anchor a table of mezze, hummus and lamb.
Order: Wood-grilled meats and mezze from the Sephardic-leaning menu.
Tip: Go family-style across the mezze and let the grill section anchor the table. The hummus and the lamb are reliable openers.
Mexican$$tobin-hillLunch and dinner, closed Monday
La Fonda on Main is the oldest continuously operating Mexican restaurant in San Antonio, opened by sisters Virginia Berry and Nannie Randall in 1932.
Order: Cheese enchiladas, mole poblano and a margarita on the hacienda patio.
Tip: Ask for a table on the covered patio. The mole poblano is the dish to order if you want something beyond Tex-Mex.