45 min west by roadJose Cuervo Express train from Guadalajara Central, or 1 hr drive on the 15D autopista
Famous for: Tequila tastings at Casa Sauza, Mundo Cuervo, and the Camino del Mezcal
Tequila town in Jalisco is the UNESCO agave landscape 45 min west of Guadalajara, with Casa Sauza, Mundo Cuervo tours and the canonical tequila tasting trail.
20 min east in metroUber 20 minutes from Centro Guadalajara, or the SITREN tour bus
Famous for: El Parian mariachi plaza, Casa Fuerte courtyard, ceramic workshops
Tlaquepaque in Guadalajara metro is the 20-minute east artisan town, with the El Parian arches, Casa Fuerte courtyard and Tapatio plates served.
25 min east in metroUber 25 minutes from Centro Guadalajara, Thursdays and Sundays for the tianguis
Famous for: Tianguis de Tonala, pottery workshops, comedores
Tonala in Guadalajara metro is the 25-minute east pottery town, with the Thursday and Sunday tianguis, the largest open-air market in Jalisco for comedores.
1 hr southDrive 1 hour south on the 23D highway, or shuttle from Guadalajara Centro
Famous for: Lakeside lunch at La Bodega, pescado blanco, mezcal pours
Ajijic and Lake Chapala is the lakeside town 1 hour south of Guadalajara, with La Bodega lunch, pescado blanco from the lake and mezcal pours on the malecon.
2 hr northeastDrive 2 hours northeast on the 80D highway
Famous for: Birria de chivo from the Los Altos region, traditional Jalisco plates
San Juan de los Lagos in Jalisco is the Los Altos pilgrimage town 2 hours northeast of Guadalajara, with traditional goat birria and Los Altos cantinas.
55 min westDrive 55 min west on the 15D autopista, between Guadalajara and Tequila
Famous for: Hacienda San Jose del Refugio (Herradura), tequila tours
Amatitan is the tequila-valley town 55 minutes west of Guadalajara, with Hacienda San Jose del Refugio for Herradura tours and Jalisco lunch plates.
4 hr west by roadDrive 4 hours west on the 200 highway, or 1 hr by air
Famous for: Pacific seafood, mariscos, agave-spirit beach bars
Puerto Vallarta from Guadalajara is the 4-hour west Pacific overnight, with mariscos, agave-spirit beach bars and Vallarta-style ceviche on the malecon.