Tip: Hire a car for the Route des Crus; public transport reaches Romanèche-Thorins but not the smaller villages.
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Vienne is 20 minutes south of Lyon by TER and combines France's finest Roman theatre with Cote Rotie, the steep Rhone Valley appellation where syrah grown.
Tip: Take the TER from Part-Dieu; domaine visits need booking a week ahead for the Cote Rotie estates.
Perouges is a walled medieval hilltop village 40 minutes east of Lyon where the Galette de Perouges, a flat caramelised brioche sold from a window counter.
Tip: Arrive before 10:00 or after 15:00 to beat the tour groups; the galette window opens from 09:00.
Bourg-en-Bresse is the capital of the Bresse chicken AOC, 55 minutes from Lyon, where the blue-legged birds with their blue-white-red colouring have held.
Tip: Book lunch at a Bressan ferme-auberge a week ahead; the Dombes ponds nearby are worth a 20-min drive.
Macon is the southern gateway to Burgundy, 65 km north of Lyon, where the Macon-Villages and Pouilly-Fuisse appellations produce crisp Chardonnay.
Tip: Hire a car at Macon station; the best Pouilly-Fuisse estates cluster around Fuisse and Solutre-Pouilly.
Annecy on the alpine lake east of Lyon runs lakeside bistros pouring Savoy white wines and serving the lake's signature fera (perch) alongside tartiflette.
Tip: The old town along Rue Sainte-Claire is the bistro strip; summer-weekend lakeside seating books a fortnight ahead.
Ile Barbe in the 9e is the Saone island just north of central Lyon, home to Philippe-Marc Jocteur's flagship bakery and a riverside park; the dining options.
Tip: Pair the Jocteur bakery stop with the Quai Pierre Scize walk; the island is small and a short visit.
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