Wine bar$$$downtownTue-Sat 17:00-21:00
An Italian-focused wine bar on City Hall Plaza with a tight programme of Italian producers and small plates that reflect the country's regional variety.
Signature pour: Natural Italian selections and Barolo
Wine focus: Italian-focused wine programme
Food: Italian small plates
Wine bar$$south-durhamMon 16:00-22:00; Tue-Wed 12:00-22:00; Thu-Sat 12:00-23:00; Sun 12:00-21:00
A French wine bar on Shannon Road with genuine aperitivo intent: European wines, vermouths and small plates. Open every day; longest-hours wine bar in Durham.
Signature pour: French natural wines and vermouths
Wine focus: French and Mediterranean wines
Food: European-style small plates
Wine bar$$$old-west-durhamTue-Sat 17:00-22:00; Sun 10:00-14:00 and 17:00-21:00
Vin Rouge's wine programme is classically structured with Burgundy, Bordeaux and Loire by the glass and a cellar list. Sunday brunch extends glass options.
Signature pour: Burgundy and Bordeaux by the glass
Wine focus: Classical French and American selections
Food: Full French bistro menu
Wine bar$$downtownTue-Thu 18:00-00:00; Fri-Sat 17:00-00:00; Sun 18:00-00:00
A wine-and-cocktail lounge on W Main Street focused on natural wines, orange and pet-nats. A rear entrance and late hours add to the atmosphere downtown.
Signature pour: Orange wines and pets-nats
Wine focus: Natural and low-intervention wines
Food: Snacks
Wine bar$$brightleafWed-Thu 11:00-21:00; Fri-Sat 11:00-22:00
A natural-wine bar at Brightleaf Square opened late 2025, focused on organic and biodynamic producers with a curated rotation and charcuterie accompaniment.
Signature pour: Rotating natural wine selection from small producers
Wine focus: Natural, organic and biodynamic wines
Food: Charcuterie and cheese
Wine bar$$downtownTue 11:00-19:00; Wed-Sat 11:00-21:00; Sun 12:00-18:00
A natural-wine shop and bar on S Roxboro Street that sells retail and poured glasses from the same lo-fi and biodynamic selection. Charcuterie accompanies.
Signature pour: Orange wines and lo-fi natural selections
Wine focus: Natural and biodynamic wines, global producers
Food: Charcuterie and cheese