The southwestern edge: Thompson's Point with Bissell Brothers' second home and Cellardoor wine tastings, plus the Stroudwater village near Portland Jetport.
Bissell Brothers Brewing at Thompson's Point opened 2013 from Peter and Noah Bissell, with the modern New England IPA program built around The Substance Ale.
Tip: The Substance is the flagship and available daily; rotating releases drop Thursday mornings.
Portland Craft Beer Festival at Thompson's Point runs the first weekend of July annually, featuring 60-plus Maine and US craft breweries pouring samples in the outdoor festival grounds.
Tip: Tickets via the operator site; food trucks at the venue. Sun shelter limited, dress for the day.